Early pregnancy lipid concentrations and the risk of gestational diabetes mellitus

Early pregnancy lipid concentrations and the risk of gestational diabetes mellitus

The objective of this study was to determine if early pregnancy maternal plasma lipid concentrations are elevated in women who later developed gestational diabetes mellitus (GDM) as compared with women who do not. Women, recruited prior to 16 weeks gestation, were followed until delivery. Maternal p...

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Veröffentlicht in:Diabetes research and clinical practice 2005-11, Vol.70 (2), p.134-142
Hauptverfasser: Enquobahrie, Daniel A., Williams, Michelle A., Qiu, Chunfang, Luthy, David A.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Body Mass Index
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Diabetes, Gestational - blood
Diabetes, Gestational - physiopathology
Dyslipidemias - blood
Dyslipidemias - complications
Dyslipidemias - physiopathology
Female
Gestational diabetes mellitus
Humans
Maternal Age
Parity
Plasma lipids
Pregnancy
Prospective Studies
Risk Factors
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Zusammenfassung:The objective of this study was to determine if early pregnancy maternal plasma lipid concentrations are elevated in women who later developed gestational diabetes mellitus (GDM) as compared with women who do not. Women, recruited prior to 16 weeks gestation, were followed until delivery. Maternal plasma lipid concentrations were measured in samples collected at 13 weeks gestation on average. Generalized linear models were used to estimate relative risks (RR) and 95% confidence intervals (95% CI). 5.5% of the cohort (47/851) developed GDM. Elevated triglyceride (TG) was positively associated with GDM risk ( p for trend
ISSN:0168-8227
1872-8227
DOI:10.1016/j.diabres.2005.03.022