Selective recognition of pyrophosphate in water using a backbone modified cyclic peptide receptor

A cyclic peptide based receptor, bearing two dipicolylamino arms complexed to zinc(II) ions, binds pyrophosphate ions with high affinity and selectivity in aqueous solution as determined using an indicator displacement assay.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2006-01 (28), p.2971-2973
Hauptverfasser:	McDonough, Matthew J, Reynolds, Aaron J, Lee, Wee Yu Gladys, Jolliffe, Katrina A
Format:	Artikel
Sprache:	eng
Schlagworte:	Diphosphates - chemistry Diphosphates - metabolism Models, Molecular Peptides, Cyclic - chemistry Peptides, Cyclic - metabolism Receptors, Peptide - chemistry Receptors, Peptide - metabolism Water - chemistry Water - metabolism Zinc - chemistry Zinc - metabolism
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Beschreibung
Zusammenfassung:	A cyclic peptide based receptor, bearing two dipicolylamino arms complexed to zinc(II) ions, binds pyrophosphate ions with high affinity and selectivity in aqueous solution as determined using an indicator displacement assay.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/b606917g