The expected performance of single nucleotide polymorphism loci in paternity testing

We discuss the utility of single nucleotide polymorphism loci for full trio and mother-unavailable paternity testing cases, in the presence of population substructure and relatedness of putative and actual fathers. We focus primarily on the expected number of loci required to gain specified probabil...

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Veröffentlicht in:	Forensic science international 2005-11, Vol.154 (2), p.167-172
1. Verfasser:	Ayres, Karen L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biological and medical sciences Female Forensic medicine Forensic sciences Gene Frequency General aspects Genetic Markers Humans Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Mismatch probability Paternity Paternity index Paternity testing Polymorphism, Single Nucleotide Probability Public health. Hygiene Public health. Hygiene-occupational medicine Single nucleotide polymorphisms SNP
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Zusammenfassung:	We discuss the utility of single nucleotide polymorphism loci for full trio and mother-unavailable paternity testing cases, in the presence of population substructure and relatedness of putative and actual fathers. We focus primarily on the expected number of loci required to gain specified probabilities of mismatches, and report the expected proportion of paternity indices greater than three threshold values for these loci.
ISSN:	0379-0738 1872-6283
DOI:	10.1016/j.forsciint.2004.10.004