One-step synthesis of low polydispersity, biotinylated poly(N-isopropylacrylamide) by ATRP

One-step synthesis of low polydispersity, biotinylated poly(N-isopropylacrylamide) by ATRP

Low polydispersity poly(N-isopropylacrylamide) with a biotin end-group was obtained in one step from a biotinylated initiator for atom transfer radical polymerization and interacted with streptavidin to generate the thermosensitive polymer-protein conjugate.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2005-10 (37), p.4702-4704
Hauptverfasser: Bontempo, Debora, Li, Ronald C, Ly, Tiffany, Brubaker, Carrie E, Maynard, Heather D
Format: Artikel
Sprache:eng
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Zusammenfassung:Low polydispersity poly(N-isopropylacrylamide) with a biotin end-group was obtained in one step from a biotinylated initiator for atom transfer radical polymerization and interacted with streptavidin to generate the thermosensitive polymer-protein conjugate.
ISSN:1359-7345
1364-548X
DOI:10.1039/b507912h