Multifocal Osteosarcoma Involving Unusual Sites

We report a rare case of multifocal osteosarcoma (MFOS) with involvement of skeleton, lung, bone marrow, and soft tissues, presenting with paraparesis, cranial nerve palsies, subcutaneous nodules, anemia, and thrombocytopenia. MFOS with involvement of unusual sites presents problems in diagnosis and...

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Veröffentlicht in:	Cancer investigation 2006-04, Vol.24 (3), p.278-282
Hauptverfasser:	Bhutani, Manisha, Pathak, Ashutosh Kumar, Sengar, Manju, Gupta, S. Datta, Jain, Paresh, Thulkar, Sanjay, Kochupillai, Vinod
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anemia - etiology Anemia - physiopathology Bone Marrow Neoplasms - secondary Bone Neoplasms - complications Bone Neoplasms - pathology Bone Neoplasms - physiopathology Cranial Nerve Diseases - etiology Cranial Nerve Diseases - physiopathology Diagnosis, Differential Humans Leukemia - pathology Lung Neoplasms - secondary Lymphoma - pathology Male Osteosarcoma - complications Osteosarcoma - pathology Osteosarcoma - physiopathology Paraparesis - etiology Paraparesis - physiopathology Sarcoma, Ewing - pathology Soft Tissue Neoplasms - secondary
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Zusammenfassung:	We report a rare case of multifocal osteosarcoma (MFOS) with involvement of skeleton, lung, bone marrow, and soft tissues, presenting with paraparesis, cranial nerve palsies, subcutaneous nodules, anemia, and thrombocytopenia. MFOS with involvement of unusual sites presents problems in diagnosis and has a poor prognosis. The literature on 11 cases of MFOS with extraosseus, extrapulmonary involvement reported previously has been reviewed.
ISSN:	0735-7907 1532-4192
DOI:	10.1080/07357900600629559