Increase in serum resistin during weight loss in overweight subjects is related to lipid metabolism

Objective: Human resistin has been stated to influence preadipocyte cell numbers and to stimulate adipocyte triglyceride lipolysis in vivo and in vitro. However, its role in human obesity remains unclear. Design: Cross-sectional study for comparisons of lean and obese subjects, and subsequent longit...

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Veröffentlicht in:	International Journal of Obesity 2006-07, Vol.30 (7), p.1097-1103
Hauptverfasser:	Koebnick, C, Wagner, K, Garcia, A.L, Gruendel, S, Lahmann, P.H, Weickert, M.O, Mohlig, M, Harsch, I.A, Einig, C, Speth, M
Format:	Artikel
Sprache:	eng
Schlagworte:	abdominal fat adipose tissue adipose tissue-specific secretory factor Adult Biological and medical sciences blood chemistry blood lipids Body Constitution Body fat Body Fat Distribution Body mass index Body weight carbohydrate metabolism Cholesterol Cholesterol - blood Cross-Sectional Studies Eating Epidemiology Exercise Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology gender differences General aspects glucose Health Promotion and Disease Prevention hormones Humans Insulin - blood Insulin Resistance Internal Medicine Intervention Lipid Metabolism Longitudinal Studies Male Medical sciences Medicine Medicine & Public Health Metabolic Diseases Middle Aged Nutrition Obesity Obesity - blood Obesity - diet therapy original-article Overweight Public Health resistin Resistin - blood Sex Factors Vertebrates: anatomy and physiology, studies on body, several organs or systems waist-to-hip ratio Weight Loss
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Beschreibung
Zusammenfassung:	Objective: Human resistin has been stated to influence preadipocyte cell numbers and to stimulate adipocyte triglyceride lipolysis in vivo and in vitro. However, its role in human obesity remains unclear. Design: Cross-sectional study for comparisons of lean and obese subjects, and subsequent longitudinal 4-month weight loss intervention study in obese subjects. Subjects: Healthy subjects, lean (n=20, BMI
ISSN:	0307-0565 1476-5497
DOI:	10.1038/sj.ijo.0803242