Granular cell tumor of the neurohypophysis : report of a case with unusual age presentation

Granular cell tumor (GCT) usually occurs as a solitary, small, nodular tumor and rarely grows to a sufficient size to present symptoms. The tumor is more prevalent in female adults. The authors report a case of an 8-year-old boy with GCT of the neurohypophysis presenting with central precocious pube...

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Veröffentlicht in:Virchows Archiv : an international journal of pathology 2005-09, Vol.447 (3), p.649-652
Hauptverfasser: FILHO, Paulo R, SAKAMOTO, Daniele, NOGUCHI, Tiago, MARIA, Machuca, SERAPIAO, José, DITZEL, Leo, BLEGGI TORRES, Luiz F
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container_issue 3
container_start_page 649
container_title Virchows Archiv : an international journal of pathology
container_volume 447
creator FILHO, Paulo R
SAKAMOTO, Daniele
NOGUCHI, Tiago
MARIA, Machuca
SERAPIAO, José
DITZEL, Leo
BLEGGI TORRES, Luiz F
description Granular cell tumor (GCT) usually occurs as a solitary, small, nodular tumor and rarely grows to a sufficient size to present symptoms. The tumor is more prevalent in female adults. The authors report a case of an 8-year-old boy with GCT of the neurohypophysis presenting with central precocious puberty. Few cases of symptomatic GCT have been reported in the literature, none of them in a patient in the first decade of life. Clinical picture, histopathological features, and histogenesis of GCT of neurohypophysis are discussed.
doi_str_mv 10.1007/s00428-005-1229-z
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subjects Biological and medical sciences
Boys
Child
Granular Cell Tumor - complications
Granular Cell Tumor - pathology
Granular Cell Tumor - physiopathology
Gynecology. Andrology. Obstetrics
Humans
Immunohistochemistry
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
Pituitary Neoplasms - complications
Pituitary Neoplasms - pathology
Pituitary Neoplasms - physiopathology
Puberal and climacteric disorders (male and female)
Puberty
Puberty, Precocious - etiology
Tomography, X-Ray Computed
Tumors
title Granular cell tumor of the neurohypophysis : report of a case with unusual age presentation
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