Granular cell tumor of the neurohypophysis : report of a case with unusual age presentation

Granular cell tumor (GCT) usually occurs as a solitary, small, nodular tumor and rarely grows to a sufficient size to present symptoms. The tumor is more prevalent in female adults. The authors report a case of an 8-year-old boy with GCT of the neurohypophysis presenting with central precocious pube...

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Veröffentlicht in:Virchows Archiv : an international journal of pathology 2005-09, Vol.447 (3), p.649-652
Hauptverfasser: FILHO, Paulo R, SAKAMOTO, Daniele, NOGUCHI, Tiago, MARIA, Machuca, SERAPIAO, José, DITZEL, Leo, BLEGGI TORRES, Luiz F
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Sprache:eng
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Zusammenfassung:Granular cell tumor (GCT) usually occurs as a solitary, small, nodular tumor and rarely grows to a sufficient size to present symptoms. The tumor is more prevalent in female adults. The authors report a case of an 8-year-old boy with GCT of the neurohypophysis presenting with central precocious puberty. Few cases of symptomatic GCT have been reported in the literature, none of them in a patient in the first decade of life. Clinical picture, histopathological features, and histogenesis of GCT of neurohypophysis are discussed.
ISSN:0945-6317
1432-2307
DOI:10.1007/s00428-005-1229-z