Are risk factors of childhood asthma predicting disease persistence in early adulthood different in the developing world?

Background:  Predictive factors of childhood asthma for favorable prognosis may differ between populations where a variety of genetic and environmental factors are present. Objectives:  To document the factors predicting disease persistence in early adulthood in Turkey. Methods:  An outpatient cohor...

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Veröffentlicht in:Allergy (Copenhagen) 2006-07, Vol.61 (7), p.869-877
Hauptverfasser: Sekerel, B. E., Civelek, E., Karabulut, E., Yildirim, S., Tuncer, A., Adalioglu, G.
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Sprache:eng
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Zusammenfassung:Background:  Predictive factors of childhood asthma for favorable prognosis may differ between populations where a variety of genetic and environmental factors are present. Objectives:  To document the factors predicting disease persistence in early adulthood in Turkey. Methods:  An outpatient cohort (n = 115) with a mean follow‐up duration of 11.4 ± 0.2 years was evaluated. Complete remission was defined as no asthma symptoms, no use of controller medication, no airflow limitation and no airway hyper‐responsiveness, and clinical remission as no symptoms and no use of controller medication, within the past year. Results:  The mean ages during referral and at the final visit were 5.8 ± 0.2 and 17.1 ± 0.2 years, respectively. Thirty‐one (27%) were in complete remission, and a further 30 (26%) in clinical remission. In multivariate logistic models, diminished airflow [forced expiratory volume in 1 s (FEV1)
ISSN:0105-4538
1398-9995
DOI:10.1111/j.1398-9995.2006.01082.x