Schistosome glycans and innate immunity

Schistosome glycans and innate immunity

SUMMARY Schistosome glycans induce characteristic innate immune responses in the infected host. The molecular aspects of these responses, the pathways and receptors as well as the schistosome glycans and glycoconjugates involved, form an area of intense research. The relevant schistosome glycan elem...

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Veröffentlicht in:Parasite immunology 2005-07, Vol.27 (7‐8), p.257-264
Hauptverfasser: HOKKE, C. H., YAZDANBAKHSH, M.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
glycoconjugate
helminth
Host-Parasite Interactions
Humans
Immunity, Innate
immunomodulation
lectin
Mice
Polysaccharides - chemistry
Polysaccharides - immunology
Schistosoma - immunology
Schistosoma - metabolism
Schistosomiasis - immunology
Schistosomiasis - parasitology
Schistosomiasis - physiopathology
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Zusammenfassung:SUMMARY Schistosome glycans induce characteristic innate immune responses in the infected host. The molecular aspects of these responses, the pathways and receptors as well as the schistosome glycans and glycoconjugates involved, form an area of intense research. The relevant schistosome glycan elements and the possible mechanisms through which they act on the innate immune system are discussed in this review.
ISSN:0141-9838
1365-3024
DOI:10.1111/j.1365-3024.2005.00781.x