Combination of apolipoprotein E2 and lipoprotein lipase heterozygosity causes severe hypertriglyceridemia during pregnancy

Pregnancy is a physiological condition where plasma triglyceride levels are moderately increased. This results from raised synthesis of very-low-density lipoproteins (VLDL) in response to elevated estrogen levels. The occurence of marked hypertriglyceridemia (HTG) is rare and may result from combina...

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Veröffentlicht in:	Diabetes & metabolism 2005-06, Vol.31 (3), p.295-297
Hauptverfasser:	Hiéronimus, S, Benlian, P, Bayer, P, Bongain, A, Fredenrich, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Apolipoprotein E2 Apolipoproteins E - genetics Apolipoprotéine E2 Biological and medical sciences Diabetes. Impaired glucose tolerance Disorders of blood lipids. Hyperlipoproteinemia Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Genetic Carrier Screening Grossesse Humans Hypertriglyceridemia Hypertriglyceridemia - genetics Hypertriglycéridémie Lipoprotein Lipase - genetics LPL gene mutation Medical sciences Metabolic diseases Mutation Mutation lipoprotéine lipase Pregnancy Pregnancy Complications - blood
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