Acute renal failure due to cast nephropathy in nonsecretory myeloma: a case report and review of the literature

Multiple myeloma is characterized by marrow plamacytsois, M spike in serum or urine electrophoresis and skeletal lytic lesions. The M spike may be absent in rare instances. We describe a case of myeloma cast nephropathy with acute renal failure who did not exhibit an M spike. lambda-chain staining w...

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Veröffentlicht in:	International urology and nephrology 2005-06, Vol.37 (2), p.351-353
Hauptverfasser:	Kumar, S Karthik, Sohal, Preet M, Kohli, Harbir S, Sud, Kamal, Gupta, Krishan L, Joshi, Kusum, Sakhuja, Vinay, Jha, Vivekanand
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Kidney Injury - etiology Acute Kidney Injury - pathology Humans Kidney Diseases - complications Kidney Tubules - pathology Male Middle Aged Multiple Myeloma - complications Multiple Myeloma - pathology Paraproteinemias - complications
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Zusammenfassung:	Multiple myeloma is characterized by marrow plamacytsois, M spike in serum or urine electrophoresis and skeletal lytic lesions. The M spike may be absent in rare instances. We describe a case of myeloma cast nephropathy with acute renal failure who did not exhibit an M spike. lambda-chain staining was documented on immunoperoxidase, suggesting paraprotein-related tubular damage.
ISSN:	0301-1623 1573-2584
DOI:	10.1007/s11255-004-2362-3