Longitudinal Change in Renal Function in Patients With Idiopathic Dilated Cardiomyopathy Without Renal Insufficiency at Initial Diagnosis

Background Impaired renal function is associated with poor outcomes among patients with chronic heart failure (CHF). However, the long-term changes in renal function in CHF patients without renal insufficiency at initial diagnosis remain unclear. Methods and Results Retrospective analysis of patients presenting with idiopathic dilated cardiomyopathy (IDCM) from 1984 to 2003 and who had normal renal function defined as estimated creatinine clearance (eCcr) ≥60 ml/min at the first diagnosis. Cumulative event proportions and renal insufficiency defined as eCcr