How many parkinsonian patients are suitable candidates for deep brain stimulation of subthalamic nucleus? Results of a questionnaire

Abstract We used a CAPSIT-based questionnaire to estimate the percentage of parkinsonian patients suitable for subthalamic nucleus (STN) deep brain stimulation (DBS) in a movement disorders clinic. We found that out of 641 consecutive PD patients only 1.6% fulfilled strict STN-DBS criteria. When we...

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Veröffentlicht in:Parkinsonism & related disorders 2007-12, Vol.13 (8), p.528-531
Hauptverfasser: Morgante, Letterio, Morgante, Francesca, Moro, Elena, Epifanio, Antonio, Girlanda, Paolo, Ragonese, Paolo, Antonini, Angelo, Barone, Paolo, Bonuccelli, Ubaldo, Contarino, Maria Fiorella, Capus, Livio, Ceravolo, Maria Gabriella, Marconi, Roberto, Ceravolo, Roberto, D’Amelio, Marco, Savettieri, Giovanni
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Sprache:eng
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Zusammenfassung:Abstract We used a CAPSIT-based questionnaire to estimate the percentage of parkinsonian patients suitable for subthalamic nucleus (STN) deep brain stimulation (DBS) in a movement disorders clinic. We found that out of 641 consecutive PD patients only 1.6% fulfilled strict STN-DBS criteria. When we applied more flexible criteria, the percentage of eligibility increased to 4.5%. Most patients (60%) were ineligible because they did not satisfy multiple questionnaire items. Items related to disease severity were responsible for the largest number of exclusions. This knowledge will help make decisions on resource allocation in centres wishing to start DBS surgery.
ISSN:1353-8020
1873-5126
DOI:10.1016/j.parkreldis.2006.12.013