Elucidating mouse transmission ratio distortion

Elucidating mouse transmission ratio distortion

A proportion of wild mice carry a variant region of chromosome 17 that results in severe transmission ratio distortion in males. The genetic basis of this distortion has long been enigmatic, but a recent study begins to disentangle it.

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Bibliographische Detailangaben
Veröffentlicht in:Nature genetics 2005-09, Vol.37 (9), p.924-925
1. Verfasser: Lyon, Mary F
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Chromosomes, Mammalian
Crosses, Genetic
Female
Fertility
Genetic aspects
Genetic susceptibility
GTPase-Activating Proteins - genetics
GTPase-Activating Proteins - physiology
Haplotypes
Infectious Disease Transmission, Vertical
Male
Mice
Microtubule-Associated Proteins - chemistry
Microtubule-Associated Proteins - physiology
Nuclear Proteins - chemistry
Nuclear Proteins - physiology
Physiological aspects
Spermatozoa - physiology
t-Complex Genome Region
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Beschreibung
Zusammenfassung:A proportion of wild mice carry a variant region of chromosome 17 that results in severe transmission ratio distortion in males. The genetic basis of this distortion has long been enigmatic, but a recent study begins to disentangle it.
ISSN:1061-4036
1546-1718
DOI:10.1038/ng0905-924