Invertebrate Immune Systems Specific, Quasi-Specific, or Nonspecific?

Until recently, it was widely accepted that invertebrates fail to show a high degree of specificity and memory in their immune strategies. Recent reports have challenged this view such that our understanding of the capabilities of the invertebrate immune systems needs to be reassessed. This account...

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Veröffentlicht in:The Journal of immunology (1950) 2007-12, Vol.179 (11), p.7209-7214
Hauptverfasser: Rowley, Andrew F, Powell, Adam
Format: Artikel
Sprache:eng
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Zusammenfassung:Until recently, it was widely accepted that invertebrates fail to show a high degree of specificity and memory in their immune strategies. Recent reports have challenged this view such that our understanding of the capabilities of the invertebrate immune systems needs to be reassessed. This account critically reviews the available evidence that suggests the existence of a high degree of memory and specificity in some invertebrates and seeks mechanistic explanations of such observations. It is postulated that elevated levels of phagocytosis may be a partial explanation for this phenomenon.
ISSN:0022-1767
1550-6606
DOI:10.4049/jimmunol.179.11.7209