Gold(I)-Catalyzed Synthesis of Highly Substituted Furans

Gold(I)-Catalyzed Synthesis of Highly Substituted Furans

Cationic triphenylphosphinegold(I) complexes are excellent catalysts for a cascade reaction of propargyl-Claisen rearrangement and heterocyclization to synthesize tri- and tetrasubstituted furans. Starting from easily accessed propargyl vinyl ethers, the furans are obtained in 72−99% yield.

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Veröffentlicht in:Organic letters 2005-09, Vol.7 (18), p.3925-3927
Hauptverfasser: Suhre, Michael H, Reif, Michael, Kirsch, Stefan F
Format: Artikel
Sprache:eng
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Zusammenfassung:Cationic triphenylphosphinegold(I) complexes are excellent catalysts for a cascade reaction of propargyl-Claisen rearrangement and heterocyclization to synthesize tri- and tetrasubstituted furans. Starting from easily accessed propargyl vinyl ethers, the furans are obtained in 72−99% yield.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol0514101