Two new highly polymorphic markers in the 3′ UTR region of the PLA2G7 gene

Summary We described two new highly polymorphic markers located 31 bp downstream of the last nucleotide of exon 12 in the 3′ UTR region of the gene PLA2G7: 1344 +31TGn AGm. Eight and 14 alleles were observed for the AG and TG repeats, respectively. These two markers have the highest heterozygosity u...

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Veröffentlicht in:	International journal of immunogenetics 2007-12, Vol.34 (6), p.465-468
Hauptverfasser:	Lira, M. Gomez, Provezza, L., Terranova, C., Martinelli, N., Bozzini, C., Pignatti, P. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Alkyl-2-acetylglycerophosphocholine Esterase 3' Untranslated Regions Alleles Coronary Artery Disease - genetics Gene Frequency Genetic Markers Humans Phospholipases A2 - genetics Polymorphism, Genetic Tandem Repeat Sequences
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Zusammenfassung:	Summary We described two new highly polymorphic markers located 31 bp downstream of the last nucleotide of exon 12 in the 3′ UTR region of the gene PLA2G7: 1344 +31TGn AGm. Eight and 14 alleles were observed for the AG and TG repeats, respectively. These two markers have the highest heterozygosity until now reported for PLA2G7 gene.
ISSN:	1744-3121 1744-313X
DOI:	10.1111/j.1744-313X.2007.00710.x