Effect of plant extracts on trans-sialidase activity in human blood plasma
We studied the effects of plant extracts and products of their biological treatment on trans-sialidase activity in human blood plasma. Extracts of kelp, fucus, yarrow, Saint John's wort, onion, and honey in vitro decreased trans-sialidase activity. Extracts of pollen (beebread) and garlic powde...
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| Veröffentlicht in: | Bulletin of experimental biology and medicine 2007-01, Vol.143 (1), p.46-50 |
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| container_title | Bulletin of experimental biology and medicine |
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| creator | Aksenov, D V Kaplun, V V Tertov, V V Sobenin, I A Orekhov, A N |
| description | We studied the effects of plant extracts and products of their biological treatment on trans-sialidase activity in human blood plasma. Extracts of kelp, fucus, yarrow, Saint John's wort, onion, and honey in vitro decreased trans-sialidase activity. Extracts of pollen (beebread) and garlic powder produced the maximum inhibitory effect. trans-Sialidase activity of blood plasma ex vivo decreased 2-fold after peroral administration of pollen and garlic powder. A correlation was found between the decrease in trans-sialidase activity in blood plasma and ability of blood plasma to induce cholesterol accumulation in cultured cells from the intact human aortic intima. |
| doi_str_mv | 10.1007/s10517-007-0013-2 |
| format | Article |
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Extracts of kelp, fucus, yarrow, Saint John's wort, onion, and honey in vitro decreased trans-sialidase activity. Extracts of pollen (beebread) and garlic powder produced the maximum inhibitory effect. trans-Sialidase activity of blood plasma ex vivo decreased 2-fold after peroral administration of pollen and garlic powder. 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A correlation was found between the decrease in trans-sialidase activity in blood plasma and ability of blood plasma to induce cholesterol accumulation in cultured cells from the intact human aortic intima.</description><subject>Aorta - cytology</subject><subject>Cells, Cultured</subject><subject>Cholesterol - metabolism</subject><subject>Eukaryota - chemistry</subject><subject>Glycoproteins - blood</subject><subject>Honey</subject><subject>Humans</subject><subject>Neuraminidase - blood</subject><subject>Plant Extracts - pharmacology</subject><subject>Pollen - chemistry</subject><subject>Tunica Intima - metabolism</subject><issn>0007-4888</issn><issn>1573-8221</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNpdUE1LxDAQDaK46-oP8CLBg7dqJk2a5CjL-sWCFz2HNE2wS9usTSvuv9-UXRA8DPNm5r3H8BC6BnIPhIiHCISDyBJMBXlGT9AcuMgzSSmcojmZLkxKOUMXMW6mkRRwjmYgCSgCZI7eVt47O-Dg8bYx3YDd79AbO0QcOpxQF7NYm6auTHQ47eufetjhusNfY2s6XDYhVJMytuYSnXnTRHd17Av0-bT6WL5k6_fn1-XjOrM5LYYsV0IKVpTCeFkyUXnBGWeKcklLo7iz4BUVleOeKMqUtUBYUcnKEmfAOJ4v0N3Bd9uH79HFQbd1tK5J77swRl1ITkTBJuLtP-ImjH2XftMUcsaUVCqR4ECyfYixd15v-7o1_U4D0VPK-pCynuCUsqZJc3M0HsvWVX-KY6z5HpgBdrs</recordid><startdate>200701</startdate><enddate>200701</enddate><creator>Aksenov, D V</creator><creator>Kaplun, V V</creator><creator>Tertov, V V</creator><creator>Sobenin, I A</creator><creator>Orekhov, A N</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>200701</creationdate><title>Effect of plant extracts on trans-sialidase activity in human blood plasma</title><author>Aksenov, D V ; 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| subjects | Aorta - cytology Cells, Cultured Cholesterol - metabolism Eukaryota - chemistry Glycoproteins - blood Honey Humans Neuraminidase - blood Plant Extracts - pharmacology Pollen - chemistry Tunica Intima - metabolism |
| title | Effect of plant extracts on trans-sialidase activity in human blood plasma |
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