Effect of plant extracts on trans-sialidase activity in human blood plasma
We studied the effects of plant extracts and products of their biological treatment on trans-sialidase activity in human blood plasma. Extracts of kelp, fucus, yarrow, Saint John's wort, onion, and honey in vitro decreased trans-sialidase activity. Extracts of pollen (beebread) and garlic powde...
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Veröffentlicht in: | Bulletin of experimental biology and medicine 2007-01, Vol.143 (1), p.46-50 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | We studied the effects of plant extracts and products of their biological treatment on trans-sialidase activity in human blood plasma. Extracts of kelp, fucus, yarrow, Saint John's wort, onion, and honey in vitro decreased trans-sialidase activity. Extracts of pollen (beebread) and garlic powder produced the maximum inhibitory effect. trans-Sialidase activity of blood plasma ex vivo decreased 2-fold after peroral administration of pollen and garlic powder. A correlation was found between the decrease in trans-sialidase activity in blood plasma and ability of blood plasma to induce cholesterol accumulation in cultured cells from the intact human aortic intima. |
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ISSN: | 0007-4888 1573-8221 |
DOI: | 10.1007/s10517-007-0013-2 |