Effect of plant extracts on trans-sialidase activity in human blood plasma

We studied the effects of plant extracts and products of their biological treatment on trans-sialidase activity in human blood plasma. Extracts of kelp, fucus, yarrow, Saint John's wort, onion, and honey in vitro decreased trans-sialidase activity. Extracts of pollen (beebread) and garlic powde...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2007-01, Vol.143 (1), p.46-50
Hauptverfasser: Aksenov, D V, Kaplun, V V, Tertov, V V, Sobenin, I A, Orekhov, A N
Format: Artikel
Sprache:eng
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Zusammenfassung:We studied the effects of plant extracts and products of their biological treatment on trans-sialidase activity in human blood plasma. Extracts of kelp, fucus, yarrow, Saint John's wort, onion, and honey in vitro decreased trans-sialidase activity. Extracts of pollen (beebread) and garlic powder produced the maximum inhibitory effect. trans-Sialidase activity of blood plasma ex vivo decreased 2-fold after peroral administration of pollen and garlic powder. A correlation was found between the decrease in trans-sialidase activity in blood plasma and ability of blood plasma to induce cholesterol accumulation in cultured cells from the intact human aortic intima.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-007-0013-2