Radiation protection of DNA and membrane in vitro by extract of Hemidesmus indicus

Radioprotective effect of H. indicus root extract on lipid peroxidation in rat liver microsomes and plasmid DNA was examined. Hemidesmus indicus (HI) root extract was found to protect microsomal membranes as evident from reduction in lipid peroxidation values. The extract could also protect DNA from...

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Veröffentlicht in:	Phytotherapy research 2005-05, Vol.19 (5), p.387-390
Hauptverfasser:	Shetty, T.K, Satav, J.G, Nair, C.K.K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antioxidant activity Biological and medical sciences DNA Damage - drug effects DNA Damage - radiation effects DNA strand breaks free radical scavenging Gamma Rays General pharmacology H. indicus Hemidesmus Intracellular Membranes - drug effects Intracellular Membranes - radiation effects lipid peroxidation Male Medical sciences Microsomes, Liver - drug effects Microsomes, Liver - radiation effects Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy Plant Extracts - administration & dosage Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant Roots plasmid DNA Plasmids - drug effects Plasmids - radiation effects Radiation-Protective Agents - administration & dosage Radiation-Protective Agents - pharmacology Radiation-Protective Agents - therapeutic use radioprotection Rats Rats, Wistar
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Zusammenfassung:	Radioprotective effect of H. indicus root extract on lipid peroxidation in rat liver microsomes and plasmid DNA was examined. Hemidesmus indicus (HI) root extract was found to protect microsomal membranes as evident from reduction in lipid peroxidation values. The extract could also protect DNA from radiation induced strand breaks. Copyright © 2005 John Wiley & Sons, Ltd.
ISSN:	0951-418X 1099-1573
DOI:	10.1002/ptr.1470