TICO: a tool for improving predictions of prokaryotic translation initiation sites

We provide the tool ‘TICO’ (Translation Initiation site COrrection) for improving the results of conventional gene finders for prokaryotic genomes with regard to exact localization of the translation initiation site (TIS). At the current state TICO provides an interface for direct post processing of...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bioinformatics 2005-09, Vol.21 (17), p.3568-3569
Hauptverfasser:	Tech, Maike, Pfeifer, Nico, Morgenstern, Burkhard, Meinicke, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Base Sequence Biological and medical sciences Codon, Initiator - genetics Fundamental and applied biological sciences. Psychology General aspects Genome, Bacterial Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Molecular Sequence Data Prokaryotic Cells Protein Biosynthesis - genetics Sequence Analysis, DNA - methods Software
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	We provide the tool ‘TICO’ (Translation Initiation site COrrection) for improving the results of conventional gene finders for prokaryotic genomes with regard to exact localization of the translation initiation site (TIS). At the current state TICO provides an interface for direct post processing of the predictions obtained from the widely used program GLIMMER. Our program is based on a clustering algorithm for completely unsupervised scoring of potential TIS locations. Availability: Our tool can be freely accessed through a web interface at http://tico.gobics.de/ Contact: maike@gobics.de
ISSN:	1367-4803 1460-2059 1367-4811
DOI:	10.1093/bioinformatics/bti563