A preliminary analysis of the process of protein secretion and the diversity of putative secreted hydrolases encoded in Aspergillus fumigatus: insights from the genome

The genome sequence of Aspergillus fumigatus has enabled the annotation of genes likely to encode secreted enzymes that may be important in underpinning the natural lifestyle of the fungus and its pathogenicity. We summarize the data from the genome sequence relevant to both the process of protein s...

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Veröffentlicht in:	Medical mycology (Oxford) 2005-05, Vol.43 (S1), p.41-47
Hauptverfasser:	Robson, G. D., Huang, J., Wortman, J., Archer, D. B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aspergillosis - microbiology Aspergillosis, Allergic Bronchopulmonary - microbiology Aspergillus fumigatus Aspergillus fumigatus - enzymology Aspergillus fumigatus - genetics Aspergillus fumigatus - pathogenicity Fungal Proteins - genetics Fungal Proteins - metabolism Genome, Fungal Humans Hydrolases - genetics Hydrolases - metabolism
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Zusammenfassung:	The genome sequence of Aspergillus fumigatus has enabled the annotation of genes likely to encode secreted enzymes that may be important in underpinning the natural lifestyle of the fungus and its pathogenicity. We summarize the data from the genome sequence relevant to both the process of protein secretion and the predicted hydrolase enzymes secreted by A. fumigatus.
ISSN:	1369-3786 1460-2709
DOI:	10.1080/13693780400024305