Improving Cell-Adhesive Properties of Recombinant Bombyx mori Silk by Incorporation of Collagen or Fibronectin Derived Peptides Produced by Transgenic Silkworms

Silk of Bombyx mori can be used as various biomaterials. Especially, it is useful as a protein for coating the surface of cell culture plates since the silk possesses a biocompatibility to the cultured cells. However, the cell-adhesive ability is weaker than collagen or fibronectin, which are used f...

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Veröffentlicht in:	Biomacromolecules 2007-11, Vol.8 (11), p.3487-3492
Hauptverfasser:	Yanagisawa, Satoshi, Zhu, Zhenghua, Kobayashi, Isao, Uchino, Keiro, Tamada, Yasushi, Tamura, Toshiki, Asakura, Tetsuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Animals, Genetically Modified Applied sciences Biological and medical sciences Biotechnology Bombyx - chemistry Bombyx - genetics Bombyx - metabolism Cell Adhesion - drug effects Cell Line Collagen - chemistry Collagen - genetics Collagen - metabolism Collagen - pharmacology Escherichia coli - genetics Escherichia coli - metabolism Exact sciences and technology Fibronectins - chemistry Fibronectins - genetics Fibronectins - metabolism Fibronectins - pharmacology Fundamental and applied biological sciences. Psychology Genetic engineering Genetic technics Methods. Procedures. Technologies Mice Molecular Sequence Data Mutation - genetics Natural polymers Oligopeptides - genetics Oligopeptides - metabolism Oligopeptides - pharmacology Peptide Fragments - chemistry Peptide Fragments - genetics Peptide Fragments - metabolism Peptide Fragments - pharmacology Physicochemistry of polymers Proteins Recombinant Proteins - genetics Recombinant Proteins - metabolism Silk - genetics Silk - metabolism Transgenic animals Transgenic animals and transgenic plants
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