Detection of human bocavirus in children with Kawasaki disease

Human bocavirus (HboV) is an emerging virus that has been implicated as a cause of acute upper and lower respiratory tract infection in children. As no serological assay is available, PCR was used to screen nasopharyngeal, serum or stool samples from 16 patients with Kawasaki disease for HBoV nuclei...

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Veröffentlicht in:	Clinical microbiology and infection 2007-12, Vol.13 (12), p.1220-1222
Hauptverfasser:	Catalano-Pons, C., Giraud, C., Rozenberg, F., Meritet, J.-F., Lebon, P., Gendrel, D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Bocavirus - isolation & purification Child Childhood infections diagnosis Feces - virology human bocavirus Humans Infant Kawasaki disease Male Medical sciences Mucocutaneous Lymph Node Syndrome - complications Mucocutaneous Lymph Node Syndrome - virology Nasopharynx - virology Parvoviridae Infections - complications Parvoviridae Infections - virology PCR Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Serum - virology
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Beschreibung
Zusammenfassung:	Human bocavirus (HboV) is an emerging virus that has been implicated as a cause of acute upper and lower respiratory tract infection in children. As no serological assay is available, PCR was used to screen nasopharyngeal, serum or stool samples from 16 patients with Kawasaki disease for HBoV nucleic acid. HBoV was identified by PCR in five (31.2%) patients, suggesting that this emerging virus may also play a pathogenic role in some cases of Kawasaki disease.
ISSN:	1198-743X 1469-0691
DOI:	10.1111/j.1469-0691.2007.01827.x