Gamma irradiation does not affect 7-day storage of platelet concentrates

Background and Objectives  Extension of storage of leucocyte‐reduced platelet concentrates (LR‐PCs) to 7 days has recently been introduced, but the effect of gamma irradiation on in vitro parameters was unknown. Materials and Methods  A paired experiment was carried out, with gamma irradiation on da...

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Veröffentlicht in:Vox sanguinis 2005-08, Vol.89 (2), p.97-99
Hauptverfasser: Van Der Meer, P. F., Pietersz, R. N. I.
Format: Artikel
Sprache:eng
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Zusammenfassung:Background and Objectives  Extension of storage of leucocyte‐reduced platelet concentrates (LR‐PCs) to 7 days has recently been introduced, but the effect of gamma irradiation on in vitro parameters was unknown. Materials and Methods  A paired experiment was carried out, with gamma irradiation on day 1 or day 5 with 25 Gy, and no irradiation served as a reference. Results  Measurements during storage up to 8 days after blood collection showed no significant differences of irradiated LR‐PCs vs. the control. Conclusions  Irradiation, either on day 1 or day 5, had no effect on platelet quality during a 7‐day storage period.
ISSN:0042-9007
1423-0410
DOI:10.1111/j.1423-0410.2005.00647.x