Transcriptional changes during neuronal death and replacement in the olfactory epithelium

The olfactory epithelium has the unusual ability to replace its neurons. We forced replacement of mouse olfactory sensory neurons by bulbectomy. Microarray, bioinformatics, and in situ hybridization techniques detected a rapid shift in favor of pro-apoptotic proteins, a progressive immune response b...

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Veröffentlicht in:Molecular and cellular neuroscience 2005-09, Vol.30 (1), p.90-107
Hauptverfasser: Shetty, Ranjit S., Bose, Soma C., Nickell, Melissa D., McIntyre, Jeremy C., Hardin, Debra H., Harris, Andrew M., McClintock, Timothy S.
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Sprache:eng
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