Simple iron-amine catalysts for the cross-coupling of aryl Grignards with alkyl halides bearing beta-hydrogens

Simple iron-amine catalysts for the cross-coupling of aryl Grignards with alkyl halides bearing beta-hydrogens

Mixtures of iron(III) chloride and appropriate amine ligands are active catalysts for the coupling of aryl Grignard reagents with primary and secondary alkyl halide substrates bearing beta-hydrogens, under mild and simple reaction conditions.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2005-09 (33), p.4161-4163
Hauptverfasser: Bedford, Robin B, Bruce, Duncan W, Frost, Robert M, Hird, Michael
Format: Artikel
Sprache:eng
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Zusammenfassung:Mixtures of iron(III) chloride and appropriate amine ligands are active catalysts for the coupling of aryl Grignard reagents with primary and secondary alkyl halide substrates bearing beta-hydrogens, under mild and simple reaction conditions.
ISSN:1359-7345
1364-548X
DOI:10.1039/b507133j