A HPLC method for the simultaneous determination of seven anthracyclines
A HPLC method has been developed for the determination of epirubicin hydrochloride, doxorubicin hydrochloride and idarubicin hydrochloride in the presence of four other anthracyclines. This method ensures the rapid determination of seven anthracyclines. It is simple and rapid and does not require an...
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| Veröffentlicht in: | Journal of pharmaceutical and biomedical analysis 2005-09, Vol.39 (1), p.305-309 |
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| container_end_page | 309 |
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| container_issue | 1 |
| container_start_page | 305 |
| container_title | Journal of pharmaceutical and biomedical analysis |
| container_volume | 39 |
| creator | Badea, Irinel Lazăr, Lelia Moja, Dana Nicolescu, Daniela Tudose, Aurel |
| description | A HPLC method has been developed for the determination of epirubicin hydrochloride, doxorubicin hydrochloride and idarubicin hydrochloride in the presence of four other anthracyclines. This method ensures the rapid determination of seven anthracyclines. It is simple and rapid and does not require any preliminary treatment of the sample. The method was fully validated. |
| doi_str_mv | 10.1016/j.jpba.2005.03.039 |
| format | Article |
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This method ensures the rapid determination of seven anthracyclines. It is simple and rapid and does not require any preliminary treatment of the sample. The method was fully validated.</description><identifier>ISSN: 0731-7085</identifier><identifier>EISSN: 1873-264X</identifier><identifier>DOI: 10.1016/j.jpba.2005.03.039</identifier><identifier>PMID: 15935598</identifier><identifier>CODEN: JPBADA</identifier><language>eng</language><publisher>Amsterdam: Elsevier B.V</publisher><subject>Analysis ; Analytical, structural and metabolic biochemistry ; Anthracyclines ; Anthracyclines - analysis ; Biological and medical sciences ; Chromatography, High Pressure Liquid - methods ; Doxorubicin hydrochloride ; Epirubicin hydrochloride ; Fundamental and applied biological sciences. Psychology ; General pharmacology ; HPLC ; Idarubicin hydrochloride ; Medical sciences ; Pharmaceutical Preparations - chemistry ; Pharmacology. 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This method ensures the rapid determination of seven anthracyclines. It is simple and rapid and does not require any preliminary treatment of the sample. The method was fully validated.</description><subject>Analysis</subject><subject>Analytical, structural and metabolic biochemistry</subject><subject>Anthracyclines</subject><subject>Anthracyclines - analysis</subject><subject>Biological and medical sciences</subject><subject>Chromatography, High Pressure Liquid - methods</subject><subject>Doxorubicin hydrochloride</subject><subject>Epirubicin hydrochloride</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General pharmacology</subject><subject>HPLC</subject><subject>Idarubicin hydrochloride</subject><subject>Medical sciences</subject><subject>Pharmaceutical Preparations - chemistry</subject><subject>Pharmacology. 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Psychology</topic><topic>General pharmacology</topic><topic>HPLC</topic><topic>Idarubicin hydrochloride</topic><topic>Medical sciences</topic><topic>Pharmaceutical Preparations - chemistry</topic><topic>Pharmacology. Drug treatments</topic><topic>Reproducibility of Results</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Badea, Irinel</creatorcontrib><creatorcontrib>Lazăr, Lelia</creatorcontrib><creatorcontrib>Moja, Dana</creatorcontrib><creatorcontrib>Nicolescu, Daniela</creatorcontrib><creatorcontrib>Tudose, Aurel</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pharmaceutical and biomedical analysis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Badea, Irinel</au><au>Lazăr, Lelia</au><au>Moja, Dana</au><au>Nicolescu, Daniela</au><au>Tudose, Aurel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A HPLC method for the simultaneous determination of seven anthracyclines</atitle><jtitle>Journal of pharmaceutical and biomedical analysis</jtitle><addtitle>J Pharm Biomed Anal</addtitle><date>2005-09-01</date><risdate>2005</risdate><volume>39</volume><issue>1</issue><spage>305</spage><epage>309</epage><pages>305-309</pages><issn>0731-7085</issn><eissn>1873-264X</eissn><coden>JPBADA</coden><abstract>A HPLC method has been developed for the determination of epirubicin hydrochloride, doxorubicin hydrochloride and idarubicin hydrochloride in the presence of four other anthracyclines. This method ensures the rapid determination of seven anthracyclines. It is simple and rapid and does not require any preliminary treatment of the sample. The method was fully validated.</abstract><cop>Amsterdam</cop><pub>Elsevier B.V</pub><pmid>15935598</pmid><doi>10.1016/j.jpba.2005.03.039</doi><tpages>5</tpages></addata></record> |
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| identifier | ISSN: 0731-7085 |
| ispartof | Journal of pharmaceutical and biomedical analysis, 2005-09, Vol.39 (1), p.305-309 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Analysis Analytical, structural and metabolic biochemistry Anthracyclines Anthracyclines - analysis Biological and medical sciences Chromatography, High Pressure Liquid - methods Doxorubicin hydrochloride Epirubicin hydrochloride Fundamental and applied biological sciences. Psychology General pharmacology HPLC Idarubicin hydrochloride Medical sciences Pharmaceutical Preparations - chemistry Pharmacology. Drug treatments Reproducibility of Results |
| title | A HPLC method for the simultaneous determination of seven anthracyclines |
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