No incremental clinical information of NT Pro BNP at peak exercise over resting levels in patients with impaired left ventricular function

Albstract There is an increasing tension to use NT Pro BNP blood levels at peak exercise testing. Their possible superiority over resting levels in congestive heart failure or factors associated with their increase have not been adequately studied. We studied 65 patients, 51 males and 14 females wit...

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Veröffentlicht in:	International journal of cardiology 2007-10, Vol.121 (2), p.221-223
Hauptverfasser:	Kallistratos, M.S, Dritsas, A, Laoutaris, I.D, Cokkinos, D.V
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomarkers - blood Cardiology. Vascular system Cardiovascular Cardiovascular system Echocardiography Exercise Exercise Test - methods Female Heart Heart failure Heart failure, cardiogenic pulmonary edema, cardiac enlargement Humans Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Natriuretic Peptide, Brain - blood Natriuretic peptides Peptide Fragments - blood Rest - physiology Ultrasonic investigative techniques Ventricular Dysfunction, Left - blood Ventricular Dysfunction, Left - diagnosis Ventricular Dysfunction, Left - physiopathology
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Zusammenfassung:	Albstract There is an increasing tension to use NT Pro BNP blood levels at peak exercise testing. Their possible superiority over resting levels in congestive heart failure or factors associated with their increase have not been adequately studied. We studied 65 patients, 51 males and 14 females with impaired left ventricular function. Mean left ventricular ejection fraction (LVEF) was 35 ± 9%. Our findings suggest that in patients with heart failure NT Pro BNP plasma levels at peak exercise do not provide incremental clinical information over resting levels. Baseline NT Pro BNP alone can provide sufficient clinical information.
ISSN:	0167-5273 1874-1754
DOI:	10.1016/j.ijcard.2006.08.112