Phenotype and coronary outcome in Kawasaki's disease
More recently, using IVIG unresponsiveness as a marker for increased risk for coronary artery aneurysms, T Kobayashi and colleagues identified decreased serum sodium, increased percentage of peripheral blood neutrophils, early treatment with IVIG (on or before day 4), raised aspartate aminotransfera...
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Veröffentlicht in: | The Lancet (British edition) 2007-01, Vol.369 (9556), p.85-87 |
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description | More recently, using IVIG unresponsiveness as a marker for increased risk for coronary artery aneurysms, T Kobayashi and colleagues identified decreased serum sodium, increased percentage of peripheral blood neutrophils, early treatment with IVIG (on or before day 4), raised aspartate aminotransferase, young age, low platelet count, and high C-reactivc protein as high-risk factors.10 When analysed separately, those treated early (on or before day 4 of fever) had higher risk scores than those treated later, suggesting that those treated early had more striking clinical features (which implies more intense inflammation and severe vasculitis). |
doi_str_mv | 10.1016/S0140-6736(07)60045-2 |
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subjects | Aneurysms Arthritis Child Child, Preschool Coronary Disease - etiology Diagnostic tests Fever Genotype & phenotype Humans Infant Internal Medicine Mucocutaneous Lymph Node Syndrome - complications Mucocutaneous Lymph Node Syndrome - diagnosis Mucocutaneous Lymph Node Syndrome - physiopathology Phenotype Risk factors Veins & arteries |
title | Phenotype and coronary outcome in Kawasaki's disease |
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