Total Synthesis of Bistramide A

An asymmetric synthesis of the marine metabolite bistramide A is reported. The synthesis relies on the utility of three different organosilane reagents to construct all principle fragments and 8 of the 11 stereogenic centers of the natural product.

Bibliographische Detailangaben

Veröffentlicht in:	Organic letters 2007-01, Vol.9 (2), p.327-330
Hauptverfasser:	Lowe, Jason T, Wrona, Iwona E, Panek, James S
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetamides - chemical synthesis Acetamides - chemistry Molecular Conformation Pyrans - chemical synthesis Pyrans - chemistry Spiro Compounds - chemical synthesis Spiro Compounds - chemistry Stereoisomerism
Online-Zugang:	Volltext
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