Conformational change of membrane proteins leads to shape changes of red blood cells

High-resolution atomic force microscopy (AFM) allows a new insight into the surface of mammalian cells. Using the human red blood cell (RBC) as a model, we have demonstrated an important correlation between the conformation of membrane proteins measured from the external face of the cell and the cel...

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Veröffentlicht in:	Bioelectrochemistry (Amsterdam, Netherlands) Netherlands), 2007, Vol.70 (1), p.122-126
Hauptverfasser:	Betz, Thomas, Bakowsky, Udo, Müller, Michael R., Lehr, Claus-Michael, Bernhardt, Ingolf
Format:	Artikel
Sprache:	eng
Schlagworte:	Atomic force microscopy Cell Shape Erythrocyte Erythrocytes - cytology Erythrocytes - ultrastructure Humans Membrane Proteins - chemistry Membrane Proteins - ultrastructure Microscopy, Atomic Force Protein conformation Red blood cell
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Beschreibung
Zusammenfassung:	High-resolution atomic force microscopy (AFM) allows a new insight into the surface of mammalian cells. Using the human red blood cell (RBC) as a model, we have demonstrated an important correlation between the conformation of membrane proteins measured from the external face of the cell and the cell shape.
ISSN:	1567-5394 1878-562X
DOI:	10.1016/j.bioelechem.2006.03.019