Population data on the seven short tandem repeat loci D4S2366, D6S474, D14S608, D19S246, D20S480, D21S226 and D22S689 in a German population

Population data on the seven short tandem repeat loci D4S2366, D6S474, D14S608, D19S246, D20S480, D21S226 and D22S689 in a German population

Allele frequencies for the autosomal tetranucleotide short tandem repeat loci D4S2366, D6S474, D14S608, D19S246, D20S480, D21S226 and D22S689 were investigated in a sample of 189 unrelated German individuals using a multiplex polymerase chain reaction approach. The loci showed no significant deviati...

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Veröffentlicht in:International journal of legal medicine 2007-01, Vol.121 (1), p.78-81
Hauptverfasser: Becker, Dorit, Vogelsang, Dorit, Brabetz, Werner
Format: Artikel
Sprache:eng
Schlagworte:
Capillary electrophoresis
Chromosomes
Cloning
DNA Fingerprinting
European Continental Ancestry Group - genetics
Gene Frequency
Germany
Humans
Microsatellite Repeats - genetics
Paternity
Polymerase chain reaction
Polymorphism, Genetic - genetics
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Zusammenfassung:Allele frequencies for the autosomal tetranucleotide short tandem repeat loci D4S2366, D6S474, D14S608, D19S246, D20S480, D21S226 and D22S689 were investigated in a sample of 189 unrelated German individuals using a multiplex polymerase chain reaction approach. The loci showed no significant deviations from Hardy-Weinberg equilibrium except for D14S608. All genotyped alleles were cloned and sequenced, and an allelic nomenclature consistent with the ISFH recommendations was defined.
ISSN:0937-9827
1437-1596
DOI:10.1007/s00414-005-0060-z