Engineered muscle: a tool for studying muscle physiology and function

Engineered muscle: a tool for studying muscle physiology and function

Recent advances in skeletal muscle tissue engineering have resulted in an in vitro tissue model that can be used for studying the effects of genetic alterations, pharmacological interventions, and exercise on muscle physiology and function. Here, we present applications for this technology to furthe...

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Veröffentlicht in:Exercise and sport sciences reviews 2007-10, Vol.35 (4), p.186-191
Hauptverfasser: Khodabukus, Alastair, Paxton, Jennifer Z, Donnelly, Kenneth, Baar, Keith
Format: Artikel
Sprache:eng
Schlagworte:
Exercise - physiology
Humans
Models, Biological
Muscle Fibers, Skeletal
Muscle, Skeletal - physiology
Tissue Engineering
United Kingdom
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Zusammenfassung:Recent advances in skeletal muscle tissue engineering have resulted in an in vitro tissue model that can be used for studying the effects of genetic alterations, pharmacological interventions, and exercise on muscle physiology and function. Here, we present applications for this technology to further our understanding of the molecular mechanisms underlying skeletal muscle adaptation in response to exercise.
ISSN:0091-6331
DOI:10.1097/jes.0b013e318156df01