HIV-1 antiretroviral drug resistance in recently infected patients in Abidjan, Côte d'Ivoire : A 4-year survey, 2002-2006

We performed HIV-1 drug resistance genotypic analysis of viral isolates from 100 antiretroviral (ARV)-naive, recently HIV-1-infected (between 2002 and 2006) individuals from Abidjan (Côte d'Ivoire). The overall prevalence of HIV-1 variants with resistance mutations to reverse transcriptase, pro...

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Veröffentlicht in:AIDS research and human retroviruses 2007-09, Vol.23 (9), p.1155-1160
Hauptverfasser: D'AQUIN TONI, Thomas, MASQUELIER, Bernard, MINGA, Albert, ANGLARET, Xavier, DANEL, Christine, COULIBALY, Ali, CHENAL, Henri, DABIS, Francois, SALAMON, Roger, FLEURY, Hervé J
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Sprache:eng
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Zusammenfassung:We performed HIV-1 drug resistance genotypic analysis of viral isolates from 100 antiretroviral (ARV)-naive, recently HIV-1-infected (between 2002 and 2006) individuals from Abidjan (Côte d'Ivoire). The overall prevalence of HIV-1 variants with resistance mutations to reverse transcriptase, protease, or fusion inhibitors was 6%. The majority of isolates were CRF02_AG. Compared with a previous study carried out by our group in 2001-2002 in a similar population in Abidjan, our findings confirm the circulation and transmission of HIV-1 carrying key ARV drug resistance mutation.
ISSN:0889-2229
1931-8405
DOI:10.1089/aid.2007.0072