Analysis of antidiuretic effect of arginine-vasotocin and its analogs in primates
Intramuscular injection of synthetic analogs of arginine-vasotocin to monkeys after 3% water loading caused antidiuretic reaction, manifesting by reabsorption of osmotically free water and paralleled by significant changes in excretion of sodium or potassium ions. It is shown that synthetic analogs...
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Veröffentlicht in: | Bulletin of experimental biology and medicine 2006-12, Vol.142 (6), p.714-716 |
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creator | Buravkova, L B Larina, I M Korolkov, V I Dobrokhotov, I V Grigorev, A I |
description | Intramuscular injection of synthetic analogs of arginine-vasotocin to monkeys after 3% water loading caused antidiuretic reaction, manifesting by reabsorption of osmotically free water and paralleled by significant changes in excretion of sodium or potassium ions. It is shown that synthetic analogs can be more effective and selective than natural agonists. |
doi_str_mv | 10.1007/s10517-006-0459-7 |
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subjects | Animals Antidiuretic Agents - pharmacology Antidiuretics Arginine Vasopressin - analogs & derivatives Arginine Vasopressin - pharmacology Diuresis - drug effects Diuretics - pharmacology Ions - metabolism Macaca mulatta - physiology Male Osmolar Concentration Potassium - metabolism Reabsorption Sodium - metabolism Vasotocin Vasotocin - pharmacology |
title | Analysis of antidiuretic effect of arginine-vasotocin and its analogs in primates |
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