Collecting duct epithelium and injury: Not all cells are created equal

Studies by Butt et al. in the developing fetus provide new and timely insights into the regulation of repair and fibrosis in the injured kidney. Using a clinically relevant model, they have examined the response of the medullary collecting duct to ureteral obstruction, with some unexpected findings.

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Veröffentlicht in:Kidney international 2007-10, Vol.72 (8), p.914-915
1. Verfasser: Hewitson, T.D.
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description Studies by Butt et al. in the developing fetus provide new and timely insights into the regulation of repair and fibrosis in the injured kidney. Using a clinically relevant model, they have examined the response of the medullary collecting duct to ureteral obstruction, with some unexpected findings.
doi_str_mv 10.1038/sj.ki.5002508
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subjects Animals
Aquaporin 2 - metabolism
Carbonic Anhydrase II - metabolism
Cell Communication - physiology
Cell Differentiation - physiology
Cell Movement - physiology
Disease Models, Animal
Epithelial Cells - metabolism
Epithelial Cells - pathology
Female
Fibrosis
Kidney Medulla - embryology
Kidney Medulla - metabolism
Kidney Medulla - pathology
Kidney Tubules, Collecting - embryology
Kidney Tubules, Collecting - metabolism
Kidney Tubules, Collecting - pathology
Macaca mulatta
Mesoderm - metabolism
Mesoderm - pathology
Pregnancy
Ureteral Obstruction - metabolism
Ureteral Obstruction - pathology
title Collecting duct epithelium and injury: Not all cells are created equal
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