The function of Dmrt genes in vertebrate development: It is not just about sex

The Dmrt genes encode a large family of transcription factors whose function in sexual development has been well studied in invertebrates and vertebrates. Their expression pattern is not restricted to the developing gonads, indicating that Dmrt genes might regulate other developmental processes. Her...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Developmental biology 2007-10, Vol.310 (1), p.1-9
Hauptverfasser:	Hong, Chang-Soo, Park, Byung-Yong, Saint-Jeannet, Jean-Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caenorhabditis elegans Proteins - genetics DM domain Dmrt DNA-Binding Proteins - genetics Drosophila Proteins - genetics Evolution, Molecular Gene Expression Regulation, Developmental Gonads Human Development Humans Laterality Nasal placode Olfactory system Organ Specificity Sex determination Sex Determination Processes Sex Differentiation Sexual Behavior Somites Transcription Factors - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The Dmrt genes encode a large family of transcription factors whose function in sexual development has been well studied in invertebrates and vertebrates. Their expression pattern is not restricted to the developing gonads, indicating that Dmrt genes might regulate other developmental processes. Here we review the expression pattern of several members of this family across species and summarize recent findings on the function of a subset of these genes in non-gonadal tissues.
ISSN:	0012-1606 1095-564X
DOI:	10.1016/j.ydbio.2007.07.035