Additional Prognostic Value of Coronary Flow Reserve in Diabetic and Nondiabetic Patients With Negative Dipyridamole Stress Echocardiography by Wall Motion Criteria

Additional Prognostic Value of Coronary Flow Reserve in Diabetic and Nondiabetic Patients With Negative Dipyridamole Stress Echocardiography by Wall Motion Criteria Lauro Cortigiani, Fausto Rigo, Sonia Gherardi, Rosa Sicari, Maurizio Galderisi, Francesco Bovenzi, Eugenio Picano The prognostic value...

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Veröffentlicht in:	Journal of the American College of Cardiology 2007-10, Vol.50 (14), p.1354-1361
Hauptverfasser:	Cortigiani, Lauro, MD, Rigo, Fausto, MD, FESC, Gherardi, Sonia, MD, Sicari, Rosa, MD, PhD, FESC, Galderisi, Maurizio, MD, FESC, Bovenzi, Francesco, MD, Picano, Eugenio, MD, PhD, FESC
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cardiology Cardiology. Vascular system Cardiovascular Cardiovascular disease Cardiovascular system Confidence intervals Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - physiopathology Coronary vessels Diabetes Diabetes Complications - diagnostic imaging Diabetes Complications - physiopathology Diabetes. Impaired glucose tolerance Dipyridamole Echocardiography, Stress Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Family medical history Female Follow-Up Studies Fractional Flow Reserve, Myocardial Heart attacks Humans Hypertension Internal Medicine Investigative techniques, diagnostic techniques (general aspects) Male Medical imaging Medical sciences Middle Aged Multivariate Analysis Predictive Value of Tests Prognosis Prospective Studies Quality control Risk Assessment Studies Ultrasonic investigative techniques Vasodilator Agents
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Zusammenfassung:	Additional Prognostic Value of Coronary Flow Reserve in Diabetic and Nondiabetic Patients With Negative Dipyridamole Stress Echocardiography by Wall Motion Criteria Lauro Cortigiani, Fausto Rigo, Sonia Gherardi, Rosa Sicari, Maurizio Galderisi, Francesco Bovenzi, Eugenio Picano The prognostic value of coronary flow reserve (CFR) in diabetic patients with negative stress echocardiography remains unknown. The aim of this prospective, multicenter, observational study was to compare the prognostic value of Doppler echocardiographic-derived CFR during vasodilator stress echocardiography with dipyridamole in diabetic and nondiabetic patients with known or suspected coronary artery disease and negative dipyridamole stress echocardiography. Coronary flow reserve provides independent prognostic information in diabetic and nondiabetic patients with known or suspected coronary artery disease and negative dipyridamole stress echocardiography. In particular, a normal CFR off therapy is associated with better and similar survival in the 2 populations.
ISSN:	0735-1097 1558-3597
DOI:	10.1016/j.jacc.2007.06.027