Organocatalytic Enantioselective Friedel−Crafts Reaction of Pyrrole Derivatives with Imines

Organocatalytic Enantioselective Friedel−Crafts Reaction of Pyrrole Derivatives with Imines

A highly enantioselective Friedel−Crafts reaction of pyrrole derivatives with N-acyl imines catalyzed by chiral phosphoric acids was developed. The reactions produced the pyrrole derivatives in high yields and enantioselectivity.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Organic letters 2007-09, Vol.9 (20), p.4065-4068
Hauptverfasser: Li, Guilong, Rowland, Gerald B, Rowland, Emily B, Antilla, Jon C
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A highly enantioselective Friedel−Crafts reaction of pyrrole derivatives with N-acyl imines catalyzed by chiral phosphoric acids was developed. The reactions produced the pyrrole derivatives in high yields and enantioselectivity.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol701881j