New Sensitive Fluorophores for Selective DNA Detection

4,7-Disubstituted benzothiadiazoles containing 1-arylethynyl and 4-methoxyphenyl groups are selective photoluminescent “light up” probes to duplex DNA with unprecedented sensibility in both spectrophotometric and spectrofluorimetric measurements.

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Bibliographische Detailangaben
Veröffentlicht in:	Organic letters 2007-09, Vol.9 (20), p.4001-4004
Hauptverfasser:	Neto, Brenno A. D, Lapis, Alexandre A. M, Mancilha, Fabiana S, Vasconcelos, Igor B, Thum, Caroline, Basso, Luiz A, Santos, Diógenes S, Dupont, Jaïrton
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA - analysis DNA - chemistry Fluorescent Dyes - analysis Fluorescent Dyes - chemistry Molecular Structure Sensitivity and Specificity Spectrophotometry Titrimetry
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Beschreibung
Zusammenfassung:	4,7-Disubstituted benzothiadiazoles containing 1-arylethynyl and 4-methoxyphenyl groups are selective photoluminescent “light up” probes to duplex DNA with unprecedented sensibility in both spectrophotometric and spectrofluorimetric measurements.
ISSN:	1523-7060 1523-7052
DOI:	10.1021/ol701708y