Cholecystitis as the initial manifestation of disseminated cryptococcosis

Cryptococcus neoformans is an important fungal pathogen causing invasive infection in recent years as a result of the frequent occurrence of the disease in patients with AIDS. Disseminated cryptococcosis presenting as cholecystitis is rare. We report a 65-year-old woman with AIDS, who presented with clinical and radiological features suggestive of cholecystitis, and was ultimately found to have cryptococcal involvement of the gall bladder as part of disseminated cryptococcosis.