Infantile hemangioendothelioma of liver: report of two cases

Infantile hemangioendothelioma, the commonest mesenchymal tumour of liver in infancy, though benign in nature, may behave aggressively. Here reports of two such cases are presented. Both were girls and less than 1-year old. Grossly, they presented with nodular hepatic masses with features of heart f...

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Veröffentlicht in:	Indian journal of pathology & microbiology 2007-04, Vol.50 (2), p.340-342
Hauptverfasser:	Bhattacharyya, Nirmal Kumar, Chatterjee, Uttara, Sen, Sharmila, Sarkar, Shanti
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD34 - metabolism Female Hemangioendothelioma - metabolism Hemangioendothelioma - pathology Hemangioendothelioma - therapy Humans Immunohistochemistry Infant Keratins - metabolism Liver Neoplasms - metabolism Liver Neoplasms - pathology Liver Neoplasms - therapy
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Zusammenfassung:	Infantile hemangioendothelioma, the commonest mesenchymal tumour of liver in infancy, though benign in nature, may behave aggressively. Here reports of two such cases are presented. Both were girls and less than 1-year old. Grossly, they presented with nodular hepatic masses with features of heart failure. Histopathology of both liver masses showed intercommunicating bloodvessels, lined by single layer of plump endothelial cells showing CD-34 positivity by immunohistochemistry. Entrapped biliary channels within tumour mass showed cytokeratin positivity.
ISSN:	0377-4929