Anti-tubercular agents. Part IV: Synthesis and antimycobacterial evaluation of nitroheterocyclic-based 1,2,4-benzothiadiazines

In continuation of our earlier work on benzothiadiazines, we have prepared a series of nitrofuran, nitrothiophene and arylfuran coupled benzothiadiazines and evaluated them for antimycobacterial and antibacterial activities. One of the compounds 2f has shown good in vitro antimycobacterial activity....

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2007-10, Vol.17 (19), p.5419-5422
Hauptverfasser:	Kamal, Ahmed, Kaleem Ahmed, S., Srinivasa Reddy, K., Khan, M. Naseer A., Shetty, Rajesh V.C.R.N.C., Siddhardha, B., Murthy, U.S.N., Khan, Inshad Ali, Kumar, Manoj, Sharma, Sandeep, Ram, Anshu Beulah
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - pharmacology Antibacterial Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Antimycobacterial Antitubercular Agents - chemical synthesis Antitubercular Agents - pharmacology Arylfurans Bacteria - drug effects Benzothiadiazines Benzothiadiazines - chemical synthesis Benzothiadiazines - pharmacology Biological and medical sciences Indicators and Reagents Medical sciences Microbial Sensitivity Tests Mycobacterium tuberculosis - drug effects Nitrofuran Nitrothiophene Pharmacology. Drug treatments Structure-Activity Relationship
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