Cross-reactivity of non- Aspergillus fungal species in the Aspergillus galactomannan enzyme immunoassay

Abstract The Aspergillus galactomannan enzyme-linked immunosorbant assay (EIA) has been demonstrated to facilitate rapid and sensitive detection of invasive aspergillosis. However, test specificity has not been fully evaluated in non- Aspergillus fungal species. Of 53 fungal isolates, cross-reactivi...

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Veröffentlicht in:	Diagnostic microbiology and infectious disease 2007-09, Vol.59 (1), p.113-115
Hauptverfasser:	Cummings, Jessica R, Jamison, Ginger R, Boudreaux, Jan W, Howles, Merry J, Walsh, Thomas J, Hayden, Randall T
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigen Aspergillosis - diagnosis Aspergillus Aspergillus - classification Biological and medical sciences Blastomyces dermatitidis Cross Reactions Fundamental and applied biological sciences. Psychology Galactomannan Humans Immunoenzyme Techniques - methods Infectious Disease Internal Medicine Mannans - classification Microbiology Miscellaneous Mycological Typing Techniques - methods Mycology Mycoses - diagnosis Paecilomyces lilacinus Penicillium chrysogenum Sensitivity and Specificity
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Zusammenfassung:	Abstract The Aspergillus galactomannan enzyme-linked immunosorbant assay (EIA) has been demonstrated to facilitate rapid and sensitive detection of invasive aspergillosis. However, test specificity has not been fully evaluated in non- Aspergillus fungal species. Of 53 fungal isolates, cross-reactivity was observed with 5 non- Aspergillus spp.: Blastomyces dermatitidis , Nigrospora oryzae , Paecilomyces lilacinus , Penicillium chrysogenum , and Trichothecium roseum.
ISSN:	0732-8893 1879-0070
DOI:	10.1016/j.diagmicrobio.2007.04.022