Dexmedetomidine as sole sedative for awake intubation in management of the critical airway

Abstract We report a series of successful awake fiberoptic intubations in patients with critical (unstable, difficult) airways using the α2 -agonist, dexmedetomidine. Dexmedetomidine has several desirable pharmacologic properties, including sedation, anxiolysis, hypnosis, analgesia, amnesia, antisia...

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Veröffentlicht in:	Journal of clinical anesthesia 2007-08, Vol.19 (5), p.370-373
Hauptverfasser:	Abdelmalak, Basem, MD, Makary, Laila, MD, Hoban, Jeremy, MD, Doyle, D. John, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Airway management Airway Obstruction - complications Anesthesia Anesthesia & Perioperative Care Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Awake intubation Biological and medical sciences Conscious Sedation - methods Dexmedetomidine Difficult airway Family medical history Female Fiber Optic Technology Fiberoptic bronchoscopy Hospitals Humans Hypnotics and Sedatives Intubation Intubation, Intratracheal - methods Larynx Male Medical sciences Middle Aged Ostomy Pain Medicine Sedation Throat Wakefulness
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Zusammenfassung:	Abstract We report a series of successful awake fiberoptic intubations in patients with critical (unstable, difficult) airways using the α2 -agonist, dexmedetomidine. Dexmedetomidine has several desirable pharmacologic properties, including sedation, anxiolysis, hypnosis, analgesia, amnesia, antisialagogue effects, and a unique respiratory-sparing effect. Dexmedetomidine appears to be a useful agent for sedation during awake fiberoptic intubation in difficult airway patients.
ISSN:	0952-8180 1873-4529
DOI:	10.1016/j.jclinane.2006.09.006