Ganciclovir-resistant, cytomegalic interstitial lung disease in a patient with systemic lupus erythematosus

A patient with systemic lupus erythematosus developed interstitial lung disease initially felt to be a manifestation of the disease but that, on further workup, proved to be a manifestation of cytomegalic disease resistant to ganciclovir. Treatment with foscarnet was associated with prompt improveme...

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Veröffentlicht in:	Clinical rheumatology 2007-10, Vol.26 (10), p.1753-1755
Hauptverfasser:	Finger, Eduardo, Romaldini, Helio, Lewi, David Salomão, Scheinberg, Morton Aaron
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Agents - pharmacology Autoimmune diseases Cytomegalovirus - metabolism Cytomegalovirus Infections - complications Cytomegalovirus Infections - diagnosis Female Ganciclovir - pharmacology Humans Immunosuppression Immunosuppressive Agents - therapeutic use Lung diseases Lung Diseases, Interstitial - complications Lung Diseases, Interstitial - virology Lupus Lupus Erythematosus, Systemic - complications Lupus Erythematosus, Systemic - drug therapy Lupus Erythematosus, Systemic - virology Lupus Vulgaris - drug therapy Lupus Vulgaris - pathology Lupus Vulgaris - virology Middle Aged Pneumonia - complications Pneumonia - diagnosis Pneumonia - virology Treatment Outcome
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Zusammenfassung:	A patient with systemic lupus erythematosus developed interstitial lung disease initially felt to be a manifestation of the disease but that, on further workup, proved to be a manifestation of cytomegalic disease resistant to ganciclovir. Treatment with foscarnet was associated with prompt improvement.
ISSN:	0770-3198 1434-9949
DOI:	10.1007/s10067-006-0500-2