Transport of Semiconductor Nanocrystals by Kinesin Molecular Motors

Transport of Semiconductor Nanocrystals by Kinesin Molecular Motors

Biotin‐functionalized quantum dots were synthesized and conjugated to kinesin molecular motors through a neutravidin bridging molecule (see figure). Quantum dot–kinesin complexes were visualized moving along immobilized microtubules by either total internal reflection fluorescence or epifluorescence...

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Veröffentlicht in:Small (Weinheim an der Bergstrasse, Germany) Germany), 2006-05, Vol.2 (5), p.626-630
Hauptverfasser: Muthukrishnan, Gayatri, Hutchins, Benjamin M., Williams, Mary Elizabeth, Hancock, William O.
Format: Artikel
Sprache:eng
Schlagworte:
biomolecular motors
bionanotechnology
biophysics
Crystallization - methods
Kinesin - chemistry
Kinesin - ultrastructure
Materials Testing
Microtubules - chemistry
Microtubules - ultrastructure
Molecular Conformation
molecular imaging
Molecular Motor Proteins - chemistry
Molecular Motor Proteins - ultrastructure
Motion
Nanotechnology - methods
Particle Size
Quantum Dots
Semiconductors
Surface Properties
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Beschreibung
Zusammenfassung:Biotin‐functionalized quantum dots were synthesized and conjugated to kinesin molecular motors through a neutravidin bridging molecule (see figure). Quantum dot–kinesin complexes were visualized moving along immobilized microtubules by either total internal reflection fluorescence or epifluorescence microscopy. This study provides a new approach for long‐term biomotor imaging and establishes a model for biomotor‐driven nanoparticle transport and assembly.
ISSN:1613-6810
1613-6829
DOI:10.1002/smll.200500223