An Intervention to Decrease Catheter-Related Bloodstream Infections in the ICU

Catheter-related bloodstream infections are associated with significant morbidity. In Michigan, a statewide initiative to reduce catheter-related bloodstream infections in intensive care units (ICUs) was implemented. This simple intervention included washing hands, using full-barrier precautions wit...

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Veröffentlicht in:The New England journal of medicine 2006-12, Vol.355 (26), p.2725-2732
Hauptverfasser: Pronovost, Peter, Needham, Dale, Berenholtz, Sean, Sinopoli, David, Chu, Haitao, Cosgrove, Sara, Sexton, Bryan, Hyzy, Robert, Welsh, Robert, Roth, Gary, Bander, Joseph, Kepros, John, Goeschel, Christine
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Sprache:eng
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Zusammenfassung:Catheter-related bloodstream infections are associated with significant morbidity. In Michigan, a statewide initiative to reduce catheter-related bloodstream infections in intensive care units (ICUs) was implemented. This simple intervention included washing hands, using full-barrier precautions with central-line placement, cleaning the skin with chlorhexidine, avoiding the femoral site if possible, and removing unnecessary catheters. The median rate of infection per 1000 catheter-days decreased from 2.7 at baseline to 0 throughout all periods after implementation of the study intervention. In Michigan, a statewide initiative to reduce catheter-related bloodstream infections in ICUs was implemented. The median rate of infection per 1000 catheter-days decreased from 2.7 at baseline to 0 throughout all periods after implementation of the study intervention. Catheter-related bloodstream infections are common, costly, and potentially lethal. 1 , 2 Each year in the United States, central venous catheters may cause an estimated 80,000 catheter-related bloodstream infections and, as a result, up to 28,000 deaths among patients in intensive care units (ICUs). Given that the average cost of care for a patient with this infection is $45,000, 3 such infections could cost up to $2.3 billion annually. According to the National Nosocomial Infections Surveillance (NNIS) system of the Centers for Disease Control and Prevention (CDC), the median rate of catheter-related bloodstream infection in ICUs of all types ranges from 1.8 to . . .
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMoa061115